PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription

Regulation of RNA polymerase II (RNAPII)-mediated transcription controls cellular phenotypes such as cancer. Phosphatase and tensin homologue deleted on chromosome ten (PTEN), one of the most commonly altered tumor suppressors in cancer, affects transcription via its role in antagonizing the PI3K/AK...

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Detalles Bibliográficos
Autores principales: Steinbach, Nicole, Hasson, Dan, Mathur, Deepti, Stratikopoulos, Elias E, Sachidanandam, Ravi, Bernstein, Emily, Parsons, Ramon E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582409/
https://www.ncbi.nlm.nih.gov/pubmed/31169889
http://dx.doi.org/10.1093/nar/gkz272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582409/
https://www.ncbi.nlm.nih.gov/pubmed/31169889
http://dx.doi.org/10.1093/nar/gkz272

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