Continuous‐flow Synthesis of Aryl Aldehydes by Pd‐catalyzed Formylation of Aryl Bromides Using Carbon Monoxide and Hydrogen

A continuous‐flow protocol utilizing syngas (CO and H(2)) was developed for the palladium‐catalyzed reductive carbonylation of (hetero)aryl bromides to their corresponding (hetero)aryl aldehydes. The optimization of temperature, pressure, catalyst and ligand loading, and residence time resulted in p...

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Detalles Bibliográficos
Autores principales: Hone, Christopher A., Lopatka, Pavol, Munday, Rachel, O'Kearney‐McMullan, Anne, Kappe, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582436/
https://www.ncbi.nlm.nih.gov/pubmed/30300970
http://dx.doi.org/10.1002/cssc.201802261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582436/
https://www.ncbi.nlm.nih.gov/pubmed/30300970
http://dx.doi.org/10.1002/cssc.201802261

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