Telescoped, Divergent, Chemoselective C1 and C1‐C1 Homologation of Imine Surrogates: Access to Quaternary Chloro‐ and Halomethyl‐Trifluoromethyl Aziridines

A conceptually novel, high‐yielding, mono‐ or bis‐homologation was realized with lithium halocarbenoids and enables the one‐step, fully chemocontrolled assembly of a new class of quaternary trifluoromethyl aziridines. Trifluoroacetimidoyl chlorides (TFAICs) act as convenient electrophilic platforms,...

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Detalles Bibliográficos
Autores principales: Ielo, Laura, Touqeer, Saad, Roller, Alexander, Langer, Thierry, Holzer, Wolfgang, Pace, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582437/
https://www.ncbi.nlm.nih.gov/pubmed/30548145
http://dx.doi.org/10.1002/anie.201812525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582437/
https://www.ncbi.nlm.nih.gov/pubmed/30548145
http://dx.doi.org/10.1002/anie.201812525

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