Primaquine–quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species

BACKGROUND: The challenge in anti-malarial chemotherapy is based on the emergence of resistance to drugs and the search for medicines against all stages of the life cycle of Plasmodium spp. as a therapeutic target. Nowadays, many molecules with anti-malarial activity are reported. However, few studi...

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Detalles Bibliográficos
Autores principales: Bonilla-Ramírez, Leonardo, Galiano, Silvia, Quiliano, Miguel, Aldana, Ignacio, Pabón, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582477/
https://www.ncbi.nlm.nih.gov/pubmed/31217011
http://dx.doi.org/10.1186/s12936-019-2825-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582477/
https://www.ncbi.nlm.nih.gov/pubmed/31217011
http://dx.doi.org/10.1186/s12936-019-2825-8

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