Nortropane alkaloids as pharmacological chaperones in the rescue of equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome through mitochondrial potentiation, endoplasmic reticulum stress mitigation and insulin resistance alleviation

OBJECTIVES: Equine metabolic syndrome (EMS) refers to a cluster of associated abnormalities and metabolic disorders, including insulin resistance and adiposity. The numerous biological properties of mesenchymal stem cells (MSCs), including self-renewal and multipotency, have been the subject of many...

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Detalles Bibliográficos
Autores principales: Bourebaba, Lynda, Bedjou, Fatiha, Röcken, Michael, Marycz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582509/
https://www.ncbi.nlm.nih.gov/pubmed/31215461
http://dx.doi.org/10.1186/s13287-019-1292-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582509/
https://www.ncbi.nlm.nih.gov/pubmed/31215461
http://dx.doi.org/10.1186/s13287-019-1292-z

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