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SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathway

BACKGROUND: To investigate the effects of serum amyloid A1 (SAA1) on lipopolysaccharide (LPS) -induced inflammation in vascular smooth muscle cells (VSMCs). SAA1 expression was detected in LPS induced VSMCs at different concentrations for different time by using Western blotting. After pre-incubatio...

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Detalles Bibliográficos
Autores principales: Yu, Mei-Hong, Li, Xi, Li, Qian, Mo, Shi-Jing, Ni, Yin, Han, Fang, Wang, Yi-Bin, Tu, Yue-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582534/
https://www.ncbi.nlm.nih.gov/pubmed/31216990
http://dx.doi.org/10.1186/s12860-019-0197-0