Cholecystokinin type B receptor-mediated inhibition of A-type K(+) channels enhances sensory neuronal excitability through the phosphatidylinositol 3-kinase and c-Src-dependent JNK pathway

BACKGROUND: Cholecystokinin (CCK) is implicated in the regulation of nociceptive sensitivity of primary afferent neurons. Nevertheless, the underlying cellular and molecular mechanisms remain unknown. METHODS: Using patch clamp recording, western blot analysis, immunofluorescent labelling, enzyme-li...

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Detalles Bibliográficos
Autores principales: Yu, Shumin, Zhang, Yuan, Zhao, Xianyang, Chang, Zhigang, Wei, Yuan, Sun, Yufang, Jiang, Dongsheng, Jiang, Xinghong, Tao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582535/
https://www.ncbi.nlm.nih.gov/pubmed/31215470
http://dx.doi.org/10.1186/s12964-019-0385-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582535/
https://www.ncbi.nlm.nih.gov/pubmed/31215470
http://dx.doi.org/10.1186/s12964-019-0385-8

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