MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer

BACKGROUND: Chemo-resistance is one of the major challenges in the therapy of small cell lung cancer (SCLC). Multiple mechanisms are thought to be involved in chemo-resistance during SCLC treatment, but unfortunately, these mechanisms have not been well elucidated. Herein, we investigated the role o...

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Detalles Bibliográficos
Autores principales: Lai, Jinzhi, Yang, Hainan, Zhu, Yanyang, Ruan, Mei, Huang, Yayu, Zhang, Qiuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582543/
https://www.ncbi.nlm.nih.gov/pubmed/31215481
http://dx.doi.org/10.1186/s12885-019-5798-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582543/
https://www.ncbi.nlm.nih.gov/pubmed/31215481
http://dx.doi.org/10.1186/s12885-019-5798-7

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