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miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats

BACKGROUND: Radiation exposure negatively affects the regenerative ability and makes reconstruction of bone defects after tumor section difficult. miR-34a is involved in radiation biology and bone metabolism. The aim of this study was to investigate whether miR-34a could contribute to bone regenerat...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Dong, Yan, Feng, Xiaoke, Li, Liya, Jiao, Yang, Bai, Shizhu, Feng, Zhihong, Yu, Hao, Li, Xuejian, Zhao, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582588/
https://www.ncbi.nlm.nih.gov/pubmed/31215466
http://dx.doi.org/10.1186/s13287-019-1285-y