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miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats
BACKGROUND: Radiation exposure negatively affects the regenerative ability and makes reconstruction of bone defects after tumor section difficult. miR-34a is involved in radiation biology and bone metabolism. The aim of this study was to investigate whether miR-34a could contribute to bone regenerat...
Autores principales: | Liu, Huan, Dong, Yan, Feng, Xiaoke, Li, Liya, Jiao, Yang, Bai, Shizhu, Feng, Zhihong, Yu, Hao, Li, Xuejian, Zhao, Yimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582588/ https://www.ncbi.nlm.nih.gov/pubmed/31215466 http://dx.doi.org/10.1186/s13287-019-1285-y |
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