High expression of metabolic enzyme PFKFB4 is associated with poor prognosis of operable breast cancer

BACKGROUND: Enhanced glycolysis in tumors, known as the Warburg effect, provides the metabolic basis of enhanced cancer cell proliferation and metastasis. The Warburg pathway enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is a newly identified key kinase that regulates transc...

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Detalles Bibliográficos
Autores principales: Yao, Ling, Wang, Lei, Cao, Zhi-Gang, Hu, Xin, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582605/
https://www.ncbi.nlm.nih.gov/pubmed/31244553
http://dx.doi.org/10.1186/s12935-019-0882-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582605/
https://www.ncbi.nlm.nih.gov/pubmed/31244553
http://dx.doi.org/10.1186/s12935-019-0882-2

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