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High expression of metabolic enzyme PFKFB4 is associated with poor prognosis of operable breast cancer
BACKGROUND: Enhanced glycolysis in tumors, known as the Warburg effect, provides the metabolic basis of enhanced cancer cell proliferation and metastasis. The Warburg pathway enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is a newly identified key kinase that regulates transc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582605/ https://www.ncbi.nlm.nih.gov/pubmed/31244553 http://dx.doi.org/10.1186/s12935-019-0882-2 |