Impact of Integrase Inhibition Compared With Nonnucleoside Inhibition on HIV Reservoirs in Lymphoid Tissues

BACKGROUND: HIV is produced in lymphoid tissues (LT) and stored on the follicular dendritic cell network in LT. When antiretroviral therapy is started, plasma viremia decays in 2 phases; the first within days of starting therapy and the second over weeks. Raltegravir (RAL), an integrase inhibitor, h...

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Detalles Bibliográficos
Autores principales: Rothenberger, Meghan, Nganou-Makamdop, Krystelle, Kityo, Cissy, Ssali, Francis, Chipman, Jeffrey G., Beilman, Gregory J., Hoskuldsson, Torfi, Anderson, Jodi, Jasurda, Jake, Schmidt, Thomas E., Calisto, Samuel P., Pearson, Hope, Reimann, Thomas, David, Caitlin, Perkey, Katherine, Southern, Peter, Wietgrefe, Steve, Helgeson, Erika, Reilly, Cavan, Haase, Ashley T., Douek, Daniel C, Fletcher, Courtney V., Schacker, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2019
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582649/
https://www.ncbi.nlm.nih.gov/pubmed/31192893
http://dx.doi.org/10.1097/QAI.0000000000002026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582649/
https://www.ncbi.nlm.nih.gov/pubmed/31192893
http://dx.doi.org/10.1097/QAI.0000000000002026

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