Scn2a Haploinsufficiency in Mice Suppresses Hippocampal Neuronal Excitability, Excitatory Synaptic Drive, and Long-Term Potentiation, and Spatial Learning and Memory

Nav1.2, a voltage-gated sodium channel subunit encoded by the Scn2a gene, has been implicated in various brain disorders, including epilepsy, autism spectrum disorder, intellectual disability, and schizophrenia. Nav1.2 is known to regulate the generation of action potentials in the axon initial segm...

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Detalles Bibliográficos
Autores principales: Shin, Wangyong, Kweon, Hanseul, Kang, Ryeonghwa, Kim, Doyoun, Kim, Kyungdeok, Kang, Muwon, Kim, Seo Yeong, Hwang, Sun Nam, Kim, Jin Yong, Yang, Esther, Kim, Hyun, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582764/
https://www.ncbi.nlm.nih.gov/pubmed/31249508
http://dx.doi.org/10.3389/fnmol.2019.00145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582764/
https://www.ncbi.nlm.nih.gov/pubmed/31249508
http://dx.doi.org/10.3389/fnmol.2019.00145

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