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Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development

The DNA replication timing program is modulated throughout development and is also one of the main factors influencing the distribution of mutation rates across the genome. However, the relationship between the mutagenic influence of replication timing and its developmental plasticity remains unexpl...

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Detalles Bibliográficos
Autores principales: Hulke, Michelle L, Siefert, Joseph C, Sansam, Christopher L, Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582765/
https://www.ncbi.nlm.nih.gov/pubmed/31076752
http://dx.doi.org/10.1093/gbe/evz098