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Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development
The DNA replication timing program is modulated throughout development and is also one of the main factors influencing the distribution of mutation rates across the genome. However, the relationship between the mutagenic influence of replication timing and its developmental plasticity remains unexpl...
Autores principales: | Hulke, Michelle L, Siefert, Joseph C, Sansam, Christopher L, Koren, Amnon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582765/ https://www.ncbi.nlm.nih.gov/pubmed/31076752 http://dx.doi.org/10.1093/gbe/evz098 |
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