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High Sensitivity Profiling of Chromatin Structure by MNase-SSP

A complete view of eukaryotic gene regulation requires that we accurately delineate how transcription factors (TFs) and nucleosomes are arranged along linear DNA in a sensitive, unbiased manner. Here we introduce MNase-SSP, a single-stranded sequencing library preparation method for nuclease-digeste...

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Detalles Bibliográficos
Autores principales: Ramani, Vijay, Qiu, Ruolan, Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582983/
https://www.ncbi.nlm.nih.gov/pubmed/30811994
http://dx.doi.org/10.1016/j.celrep.2019.02.007