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High Sensitivity Profiling of Chromatin Structure by MNase-SSP
A complete view of eukaryotic gene regulation requires that we accurately delineate how transcription factors (TFs) and nucleosomes are arranged along linear DNA in a sensitive, unbiased manner. Here we introduce MNase-SSP, a single-stranded sequencing library preparation method for nuclease-digeste...
Autores principales: | Ramani, Vijay, Qiu, Ruolan, Shendure, Jay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582983/ https://www.ncbi.nlm.nih.gov/pubmed/30811994 http://dx.doi.org/10.1016/j.celrep.2019.02.007 |
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