Characterizing the selectivity of ER α-glucosidase inhibitors

The endoplasmic reticulum (ER) contains both α-glucosidases and α-mannosidases which process the N-linked oligosaccharides of newly synthesized glycoproteins and thereby facilitate polypeptide folding and glycoprotein quality control. By acting as structural mimetics, iminosugars can selectively inh...

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Detalles Bibliográficos
Autores principales: O’Keefe, Sarah, Roebuck, Quentin P, Nakagome, Izumi, Hirono, Shuichi, Kato, Atsushi, Nash, Robert, High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Regular Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583763/
https://www.ncbi.nlm.nih.gov/pubmed/30976784
http://dx.doi.org/10.1093/glycob/cwz029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583763/
https://www.ncbi.nlm.nih.gov/pubmed/30976784
http://dx.doi.org/10.1093/glycob/cwz029

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