Cargando…

Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c(+) B-cells in the genital tract

BLyS/BAFF is recognized for its role in B-cell ontogenesis, as well as cell fate decision towards the first-line/innate marginal zone (MZ) B-cell pool. Excess BLyS/BAFF is associated with hyperglobulinemia and increased frequencies of activated precursor-like MZ B-cells. Herein, we show that HIV hig...

Descripción completa

Detalles Bibliográficos
Autores principales: Fourcade, Lyvia, Sabourin-Poirier, Catherine, Perraud, Victoire, Faucher, Marie-Claude, Chagnon-Choquet, Josiane, Labbé, Annie-Claude, Alary, Michel, Guédou, Fernand, Poudrier, Johanne, Roger, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583986/
https://www.ncbi.nlm.nih.gov/pubmed/31173604
http://dx.doi.org/10.1371/journal.ppat.1007840