In silico analysis of PFN1 related to amyotrophic lateral sclerosis

Profilin 1 (PFN1) protein plays key roles in neuronal growth and differentiation, membrane trafficking, and regulation of the actin cytoskeleton. Four natural variants of PFN1 were described as related to ALS, the most common adult-onset motor neuron disorder. However, the pathological mechanism of...

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Detalles Bibliográficos
Autores principales: Pereira, Gabriel Rodrigues Coutinho, Tellini, Giovanni Henrique Almeida Silva, De Mesquita, Joelma Freire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583998/
https://www.ncbi.nlm.nih.gov/pubmed/31216283
http://dx.doi.org/10.1371/journal.pone.0215723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583998/
https://www.ncbi.nlm.nih.gov/pubmed/31216283
http://dx.doi.org/10.1371/journal.pone.0215723

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