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Regulated Activation of the PAR Polarity Network Ensures a Timely and Specific Response to Spatial Cues

How do cells polarize at the correct time and in response to the correct cues? In the C. elegans zygote, the timing and geometry of polarization rely on a single dominant cue—the sperm centrosome—that matures at the end of meiosis and specifies the nascent posterior. Polarization requires that the c...

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Detalles Bibliográficos
Autores principales: Reich, Jacob D., Hubatsch, Lars, Illukkumbura, Rukshala, Peglion, Florent, Bland, Tom, Hirani, Nisha, Goehring, Nathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584329/
https://www.ncbi.nlm.nih.gov/pubmed/31155349
http://dx.doi.org/10.1016/j.cub.2019.04.058