Cargando…

MUS81 Inhibition Increases the Sensitivity to Therapy Effect in Epithelial Ovarian Cancer via Regulating CyclinB Pathway

MUS81 is a key endonuclease involved in homologous recombination (HR) repair after DNA double-strand damage. Structure-specific endonucleases (SSEs) plays a crucial role in DNA replication, repair and transcription, and SSEs are also important for maintaining the secondary structure of DNA; therefor...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Ailing, Zheng, Hui, Zhang, Hongqin, Sun, Jiajun, Shen, Jiabin, Deng, Minjie, Chen, Miaomiao, Lu, Renquan, Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584407/
https://www.ncbi.nlm.nih.gov/pubmed/31258731
http://dx.doi.org/10.7150/jca.30818