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Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin
Combination chemotherapy is often employed to improve therapeutic efficacies of drugs. However, traditional combination regimens often utilize drugs at or near‐their maximum tolerated doses (MTDs), elevating the risk of dose‐related toxicity and impeding their clinical success. Further, high doses o...
Autores principales: | Pusuluri, Anusha, Krishnan, Vinu, Wu, Debra, Shields, C. Wyatt, Wang, Li W., Mitragotri, Samir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584462/ https://www.ncbi.nlm.nih.gov/pubmed/31249879 http://dx.doi.org/10.1002/btm2.10129 |
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