Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins

Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication. However, their STX molecular recognition mechanisms remain unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Yen, Tien-Jui, Lolicato, Marco, Thomas-Tran, Rhiannon, Du Bois, J., Minor, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584486/
https://www.ncbi.nlm.nih.gov/pubmed/31223657
http://dx.doi.org/10.1126/sciadv.aax2650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584486/
https://www.ncbi.nlm.nih.gov/pubmed/31223657
http://dx.doi.org/10.1126/sciadv.aax2650

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