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PIWIL1 suppresses circadian rhythms through GSK3β‐induced phosphorylation and degradation of CLOCK and BMAL1 in cancer cells

Circadian rhythms are maintained by series of circadian clock proteins, and post‐translation modifications of clock proteins significantly contribute to regulating circadian clock. However, the underlying upstream mechanism of circadian genes that are responsible for circadian rhythms in cancer cell...

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Detalles Bibliográficos
Autores principales: Tan, Hao, Zhu, Yingchuan, Zheng, Xulei, Lu, Yilu, Tao, Dachang, Liu, Yunqiang, Ma, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584488/
https://www.ncbi.nlm.nih.gov/pubmed/31099187
http://dx.doi.org/10.1111/jcmm.14377