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Pigment epithelium‐derived factor peptide promotes limbal stem cell proliferation through hedgehog pathway
Expansion of limbal epithelial stem cells (LSCs) is crucial for the success of limbal transplantation. Previous studies showed that pigment epithelium‐derived peptide (PEDF) short peptide 44‐mer could effectively expand LSCs and maintain them in a stem‐cell state, but the mechanism remained unclear....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584522/ https://www.ncbi.nlm.nih.gov/pubmed/31066230 http://dx.doi.org/10.1111/jcmm.14364 |