Enhanced ROBO4 is mediated by up‐regulation of HIF‐1α/SP1 or reduction in miR‐125b‐5p/miR‐146a‐5p in diabetic retinopathy

Retinal cell damage caused by diabetes leads to retinal microvascular injury. Roundabout 4 (ROBO4) is involved in angiogenesis, which varies with the development of diabetic retinopathy (DR). Here, we explored the transcriptional regulation and microRNA‐mediated modulation of ROBO4 expression and re...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Qiaoyun, Xie, Jia'nan, Li, Ying, Liu, Yang, Su, Guanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584523/
https://www.ncbi.nlm.nih.gov/pubmed/31094072
http://dx.doi.org/10.1111/jcmm.14369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584523/
https://www.ncbi.nlm.nih.gov/pubmed/31094072
http://dx.doi.org/10.1111/jcmm.14369

Ejemplares similares