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CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse

We examined the potential value of the natural killer (NK) cell line; NK-92, as immunotherapy tool for breast cancer (BC) treatment and searched for biomarker(s) of sensitivity to NK-92-mediated cytotoxicity. The cytotoxic activity of NK-92 cells towards one breast precancerous and nine BC cell line...

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Detalles Bibliográficos
Autores principales: Taouk, Ghina, Hussein, Ola, Zekak, Moussa, Abouelghar, Ali, Al-Sarraj, Yasser, Abdelalim, Essam M., Karam, Manale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584531/
https://www.ncbi.nlm.nih.gov/pubmed/31217484
http://dx.doi.org/10.1038/s41598-019-45377-8