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Modeling sensitivity and uncertainties in platelet activation models applied on centrifugal pumps for extracorporeal life support

Two platelet activation models were studied with respect to uncertainties of model parameters and variables. The sensitivity was assessed using two direct/deterministic approaches as well as the statistical Monte Carlo method. The first two, are linear in character whereas the latter is non-linear....

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Detalles Bibliográficos
Autores principales: Fuchs, Gabriel, Berg, Niclas, Broman, L. Mikael, Prahl Wittberg, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584555/
https://www.ncbi.nlm.nih.gov/pubmed/31217491
http://dx.doi.org/10.1038/s41598-019-45121-2