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Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells

Heparanase has been implicated in many pathological conditions, especially inflammation and cancer, attributed to its degradation of heparan sulfate, a crucial component maintaining the integrity of the extracellular matrix. By silencing the heparanase gene (HPSE) in MDA‐MB‐435s melanoma cells, we i...

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Detalles Bibliográficos
Autores principales: Song, Tianyi, Spillmann, Dorothe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584584/
https://www.ncbi.nlm.nih.gov/pubmed/31044520
http://dx.doi.org/10.1111/jcmm.14349