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Aberrant MFN2 transcription facilitates homocysteine‐induced VSMCs proliferation via the increased binding of c‐Myc to DNMT1 in atherosclerosis

It is well‐established that homocysteine (Hcy) is an independent risk factor for atherosclerosis. Hcy can promote vascular smooth muscle cell (VSMC) proliferation, it plays a key role in neointimal formation and thus contribute to arteriosclerosis. However, the molecular mechanism on VSMCs prolifera...

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Detalles Bibliográficos
Autores principales: Xu, Long, Hao, Hongyi, Hao, Yinju, Wei, Guo, Li, Guizhong, Ma, Pengjun, Xu, Lingbo, Ding, Ning, Ma, Shengchao, Chen, Alex F., Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584594/
https://www.ncbi.nlm.nih.gov/pubmed/31104361
http://dx.doi.org/10.1111/jcmm.14341