Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis

Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions of EMT heterogeneity to disease progression remain a matter of debate. Here, we addressed the EMT status of ex vivo cultured circulating and disseminated tumor cells (CTCs/DTCs) in a syngeneic mouse model of meta...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Li, Junjian, Cadilha, Bruno Loureiro, Markota, Anamarija, Voigt, Cornelia, Huang, Zhe, Lin, Peter P., Wang, Daisy D., Dai, Juncheng, Kranz, Gisela, Krandick, Anna, Libl, Darko, Zitzelsberger, Horst, Zagorski, Isabella, Braselmann, Herbert, Pan, Min, Zhu, Sibo, Huang, Yuanchi, Niedermeyer, Sebastian, Reichel, Christoph A., Uhl, Bernd, Briukhovetska, Daria, Suárez, Javier, Kobold, Sebastian, Gires, Olivier, Wang, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584608/
https://www.ncbi.nlm.nih.gov/pubmed/31223646
http://dx.doi.org/10.1126/sciadv.aav4275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584608/
https://www.ncbi.nlm.nih.gov/pubmed/31223646
http://dx.doi.org/10.1126/sciadv.aav4275

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