Amelioration of obsessive-compulsive disorder in three mouse models treated with one epigenetic drug: unraveling the underlying mechanism

Mental health disorders are manifested in families, yet cannot be fully explained by classical Mendelian genetics. Changes in gene expression via epigenetics present a plausible mechanism. Anxiety often leads to avoidant behaviors which upon repetition may become habitual, maladaptive and resistant...

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Detalles Bibliográficos
Autores principales: Todorov, German, Mayilvahanan, Karthikeyan, Ashurov, David, Cunha, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584622/
https://www.ncbi.nlm.nih.gov/pubmed/31217515
http://dx.doi.org/10.1038/s41598-019-45325-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584622/
https://www.ncbi.nlm.nih.gov/pubmed/31217515
http://dx.doi.org/10.1038/s41598-019-45325-6

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