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Amelioration of obsessive-compulsive disorder in three mouse models treated with one epigenetic drug: unraveling the underlying mechanism
Mental health disorders are manifested in families, yet cannot be fully explained by classical Mendelian genetics. Changes in gene expression via epigenetics present a plausible mechanism. Anxiety often leads to avoidant behaviors which upon repetition may become habitual, maladaptive and resistant...
Autores principales: | Todorov, German, Mayilvahanan, Karthikeyan, Ashurov, David, Cunha, Catarina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584622/ https://www.ncbi.nlm.nih.gov/pubmed/31217515 http://dx.doi.org/10.1038/s41598-019-45325-6 |
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