Involvement of microRNA-34a in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration

The aging retinal pigment epithelium and oxidative stress, mediated by reactive oxygen species (ROS) accumulation, have been implicated in the mechanisms of age-related macular degeneration (AMD). The expression level of the adapter protein p66shc, a key protein that regulates cellular oxidative str...

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Detalles Bibliográficos
Autores principales: Tong, Nianting, Jin, Rong, Zhou, Zhanyu, Wu, Xingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679/
https://www.ncbi.nlm.nih.gov/pubmed/31249522
http://dx.doi.org/10.3389/fnagi.2019.00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679/
https://www.ncbi.nlm.nih.gov/pubmed/31249522
http://dx.doi.org/10.3389/fnagi.2019.00137

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