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CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI

BRCA1 C-terminal domains are found in a specialized group of 23 proteins that function in the DNA damage response to protect genomic integrity. C-terminal domain phosphatase 1 (CTDP1) is the only phosphatase with a BRCA1 C-terminal domain in the human proteome, yet direct participation in the DNA da...

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Detalles Bibliográficos
Autores principales: Hu, Wen-Feng, Krieger, Kimiko L., Lagundžin, Dragana, Li, Xueli, Cheung, Ronald S., Taniguchi, Toshiyasu, Johnson, Keith R., Bessho, Tadayoshi, Monteiro, Alvaro N. A., Woods, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584691/
https://www.ncbi.nlm.nih.gov/pubmed/31240132
http://dx.doi.org/10.1038/s41420-019-0185-3