Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer

NRF2 is emerging as a major regulator of cellular metabolism. However, most studies have been performed in cancer cells, where co-occurring mutations and tumor selective pressures complicate the influence of NRF2 on metabolism. Here we use genetically engineered, non-transformed primary murine cells...

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Detalles Bibliográficos
Autores principales: Kang, Yun Pyo, Torrente, Laura, Falzone, Aimee, Elkins, Cody M, Liu, Min, Asara, John M, Dibble, Christian C, DeNicola, Gina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
https://www.ncbi.nlm.nih.gov/pubmed/31107239
http://dx.doi.org/10.7554/eLife.45572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
https://www.ncbi.nlm.nih.gov/pubmed/31107239
http://dx.doi.org/10.7554/eLife.45572

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