Cardiac‐specific overexpression of metallothionein attenuates L‐NAME‐induced myocardial contractile anomalies and apoptosis

Hypertension contributes to the high cardiac morbidity and mortality. Although oxidative stress plays an essential role in hypertensive heart diseases, the mechanism remains elusive. Transgenic mice with cardiac overexpression of metallothionein, a heavy metal‐binding scavenger, were challenged with...

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Detalles Bibliográficos
Autores principales: Yang, Lifang, Ma, Jipeng, Tan, Ying, Zheng, Qijun, Dong, Maolong, Guo, Wei, Xiong, Lize, Yang, Jian, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584723/
https://www.ncbi.nlm.nih.gov/pubmed/31104354
http://dx.doi.org/10.1111/jcmm.14375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584723/
https://www.ncbi.nlm.nih.gov/pubmed/31104354
http://dx.doi.org/10.1111/jcmm.14375

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