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Replication fork rescue in mammalian mitochondria

Replication stalling has been associated with the formation of pathological mitochondrial DNA (mtDNA) rearrangements. Yet, almost nothing is known about the fate of stalled replication intermediates in mitochondria. We show here that replication stalling in mitochondria leads to replication fork reg...

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Detalles Bibliográficos
Autores principales: Torregrosa-Muñumer, Rubén, Hangas, Anu, Goffart, Steffi, Blei, Daniel, Zsurka, Gábor, Griffith, Jack, Kunz, Wolfram S., Pohjoismäki, Jaakko L. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584726/
https://www.ncbi.nlm.nih.gov/pubmed/31217442
http://dx.doi.org/10.1038/s41598-019-45244-6