Endocrine regulation of MFS2 by branchless controls phosphate excretion and stone formation in Drosophila renal tubules

How inorganic phosphate (Pi) homeostasis is regulated in Drosophila is currently unknown. We here identify MFS2 as a key Pi transporter in fly renal (Malpighian) tubules. Consistent with its role in Pi excretion, we found that dietary Pi induces MFS2 expression. This results in the formation of Malp...

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Detalles Bibliográficos
Autores principales: Rose, Emily, Lee, Daniela, Xiao, Emily, Zhao, Wenzhen, Wee, Mark, Cohen, Jonathan, Bergwitz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584732/
https://www.ncbi.nlm.nih.gov/pubmed/31217461
http://dx.doi.org/10.1038/s41598-019-45269-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584732/
https://www.ncbi.nlm.nih.gov/pubmed/31217461
http://dx.doi.org/10.1038/s41598-019-45269-x

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