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Endocrine regulation of MFS2 by branchless controls phosphate excretion and stone formation in Drosophila renal tubules
How inorganic phosphate (Pi) homeostasis is regulated in Drosophila is currently unknown. We here identify MFS2 as a key Pi transporter in fly renal (Malpighian) tubules. Consistent with its role in Pi excretion, we found that dietary Pi induces MFS2 expression. This results in the formation of Malp...
Autores principales: | Rose, Emily, Lee, Daniela, Xiao, Emily, Zhao, Wenzhen, Wee, Mark, Cohen, Jonathan, Bergwitz, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584732/ https://www.ncbi.nlm.nih.gov/pubmed/31217461 http://dx.doi.org/10.1038/s41598-019-45269-x |
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