Transcriptional Activation of Gstp1 by MEK/ERK Signaling Confers Chemo-Resistance to Cisplatin in Lung Cancer Stem Cells

Lung cancer management remains a challenge due to its asymptomatic and late presentation when it is metastatic. The clinical response to the first-line platinum-based chemotherapy in patients with advanced lung cancer is disappointing due to the development of chemoresistance. Chemoresistance is a c...

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Detalles Bibliográficos
Autores principales: Li, Jingyuan, Ye, Ting, Liu, Yongli, Kong, Liangsheng, Sun, Zhiwei, Liu, Doudou, Wang, Jianyu, Xing, H. Rosie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584806/
https://www.ncbi.nlm.nih.gov/pubmed/31263672
http://dx.doi.org/10.3389/fonc.2019.00476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584806/
https://www.ncbi.nlm.nih.gov/pubmed/31263672
http://dx.doi.org/10.3389/fonc.2019.00476

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