Sigma-1 Receptor Inhibition Reduces Neuropathic Pain Induced by Partial Sciatic Nerve Transection in Mice by Opioid-Dependent and -Independent Mechanisms

Sigma-1 (σ(1)) receptor antagonists are promising tools for neuropathic pain treatment, but it is unknown whether σ(1) receptor inhibition ameliorates the neuropathic signs induced by nerve transection, in which the pathophysiological mechanisms and response to drug treatment differ from other neuro...

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Detalles Bibliográficos
Autores principales: Bravo-Caparrós, Inmaculada, Perazzoli, Gloria, Yeste, Sandra, Cikes, Domagoj, Baeyens, José Manuel, Cobos, Enrique José, Nieto, Francisco Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584826/
https://www.ncbi.nlm.nih.gov/pubmed/31263413
http://dx.doi.org/10.3389/fphar.2019.00613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584826/
https://www.ncbi.nlm.nih.gov/pubmed/31263413
http://dx.doi.org/10.3389/fphar.2019.00613

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