Cargando…

Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing

[Image: see text] The discovery of CRISPR/Cas has revolutionized the field of genome editing. CRIPSR/Cas components are part of the bacterial immune system and are able to induce double-strand DNA breaks in the genome, which are resolved by endogenous DNA repair mechanisms. The most relevant of thes...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilbie, Danny, Walther, Johanna, Mastrobattista, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584901/
https://www.ncbi.nlm.nih.gov/pubmed/31099553
http://dx.doi.org/10.1021/acs.accounts.9b00106