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Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing
[Image: see text] The discovery of CRISPR/Cas has revolutionized the field of genome editing. CRIPSR/Cas components are part of the bacterial immune system and are able to induce double-strand DNA breaks in the genome, which are resolved by endogenous DNA repair mechanisms. The most relevant of thes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584901/ https://www.ncbi.nlm.nih.gov/pubmed/31099553 http://dx.doi.org/10.1021/acs.accounts.9b00106 |