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Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain

Inositol polyphosphate multikinase (IPMK), the key enzyme responsible for the synthesis of higher inositol polyphosphates and phosphatidylinositol 3, 4, 5-trisphosphate, is known to mediate various biological events, such as cellular growth and metabolism. Conditional deletion of IPMK in excitatory...

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Detalles Bibliográficos
Autores principales: Park, Jina, Park, Seung Ju, Kim, Seyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584979/
https://www.ncbi.nlm.nih.gov/pubmed/31221192
http://dx.doi.org/10.1186/s13041-019-0480-1