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Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle
BACKGROUND: Single-step genomic best linear unbiased prediction (SSGBLUP) is a comprehensive method for genomic prediction. Point estimates of marker effects from SSGBLUP are often used for genome-wide association studies (GWAS) without a formal framework of hypothesis testing. Our objective was to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584984/ https://www.ncbi.nlm.nih.gov/pubmed/31221101 http://dx.doi.org/10.1186/s12711-019-0469-3 |