Cargando…

Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

BACKGROUND: Single-step genomic best linear unbiased prediction (SSGBLUP) is a comprehensive method for genomic prediction. Point estimates of marker effects from SSGBLUP are often used for genome-wide association studies (GWAS) without a formal framework of hypothesis testing. Our objective was to...

Descripción completa

Detalles Bibliográficos
Autores principales: Aguilar, Ignacio, Legarra, Andres, Cardoso, Fernando, Masuda, Yutaka, Lourenco, Daniela, Misztal, Ignacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584984/
https://www.ncbi.nlm.nih.gov/pubmed/31221101
http://dx.doi.org/10.1186/s12711-019-0469-3