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Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice

G(o) is a member of the pertussis toxin-sensitive G(i/o) family. Despite its abundance in the central nervous system, the precise role of G(o) remains largely unknown compared to other G proteins. In the present study, we explored the functions of G(o) in the developing cerebellar cortex by deleting...

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Detalles Bibliográficos
Autores principales: Cha, Hye Lim, Choi, Jung-Mi, Oh, Huy-Hyen, Bashyal, Narayan, Kim, Sung-Soo, Birnbaumer, Lutz, Suh-Kim, Haeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585000/
https://www.ncbi.nlm.nih.gov/pubmed/31221179
http://dx.doi.org/10.1186/s13041-019-0477-9