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PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) originates from squamous epithelium of the upper aerodigestive tract and is the most common malignancy in the head and neck region. Among HNSCCs, oropharynx squamous cell carcinoma (OSCC) has a unique profile and is associated with human papi...

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Detalles Bibliográficos
Autores principales: Hirata-Nozaki, Yui, Ohkuri, Takayuki, Ohara, Kenzo, Kumai, Takumi, Nagata, Marino, Harabuchi, Shohei, Kosaka, Akemi, Nagato, Toshihiro, Ishibashi, Kei, Oikawa, Kensuke, Aoki, Naoko, Ohara, Mizuho, Harabuchi, Yasuaki, Uno, Yuji, Takei, Hidehiro, Celis, Esteban, Kobayashi, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585001/
https://www.ncbi.nlm.nih.gov/pubmed/31221178
http://dx.doi.org/10.1186/s12967-019-1957-5