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The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni

BACKGROUND: Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel (PZQ) for more than a generation. Despite its celebrated performance for treatment and control of schistosomiasis and other platyhelminth infections, praziquantel has some shortcomings and the inability of this...

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Detalles Bibliográficos
Autores principales: Gouveia, Maria João, Brindley, Paul J., Azevedo, Carlos, Gärtner, Fátima, da Costa, José M. C., Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585032/
https://www.ncbi.nlm.nih.gov/pubmed/31221193
http://dx.doi.org/10.1186/s13071-019-3566-9